Estrogen dominance in menopausal and postmenopausal women

Estrogen dominance in menopausal and postmenopausal women

Yes, estrogen dominance in menopausal and postmenopausal women is a real phenomenon, though it may seem contradictory since estrogen levels naturally decline with age. However, what matters is the balance between estrogen and progesterone, rather than just absolute estrogen levels.

Simple Scientific Explanation- Estrogen dominance occurs when estrogen levels are high relative to progesterone. During perimenopause and menopause, both estrogen and progesterone levels decline, but progesterone drops more significantly. This imbalance can lead to estrogen dominance symptoms despite lower overall estrogen levels.

Additionally, estrogen is still produced in fat cells and adrenal glands, even after menopause. If the body is exposed to xenoestrogens (environmental estrogens from plastics, pesticides, and chemicals) or has excess body fat, estrogen can remain disproportionately high relative to progesterone.

Common Symptoms in Menopausal & Postmenopausal Women

  • Weight gain, especially around the hips and abdomen
  • Hot flashes & night sweats (can be worsened by estrogen fluctuations)
  • Fatigue & brain fog
  • Mood swings, anxiety, or depression
  • Breast tenderness or fibrocystic breasts
  • Increased risk of fibroids or endometrial thickening

What Causes Estrogen Dominance at This Stage?

  1. Progesterone Decline – Since ovulation stops, progesterone production decreases drastically.
  2. Fat Tissue Producing Estrogen – Body fat continues to synthesize estrogen, keeping levels relatively high.
  3. Environmental Estrogens (Xenoestrogens) – Exposure to plastics, pesticides, and cosmetics can contribute to hormone imbalance.
  4. Liver Detoxification Issues – If the liver isn’t metabolizing estrogen efficiently, it can accumulate in the body.
  5. Chronic Stress – Stress leads to excess cortisol production, further suppressing progesterone levels.

Managing Estrogen Dominance in Menopause

  • Support liver detoxification (eats cruciferous vegetables drink plenty of water, reduce alcohol).
  • Maintain a healthy weight to reduce estrogen production from fat cells.
  • Manage stress through mindfulness, exercise, and proper sleep.
  • Reduce exposure to xenoestrogens (use glass over plastic; avoid chemical-laden personal care products).
  • Consider hormone testing (such as DUTCH testing) to assess estrogen metabolism and hormone balance.

 

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